The prussian blue in the digestive system acts as a solid ion exchanger which absorbs the caesium while releasing potassium ions.įor some substances, it is important to think of the human or animal body as being made up of several parts, each with their own affinity for the substance, and each part with a different biological half-life. This can be shortened by feeding the person prussian blue. The biological half-life of caesium in humans is between one and four months. The metabolite has a biological half-life of 4 to 16 days.ġ5 to 60 hours, in rare cases up to 190 hours. The active metabolite of fluoxetine is lipophilic and migrates slowly from the brain to the blood. A person who has ingested ethylene glycol can be treated in the same way. Note that methanol is very toxic and causes blindness and death.
In this way the oxidation of methanol to the toxic formaldehyde and formic acid in the human body can be prevented by giving an appropriate amount of ethanol to a person who has ingested methanol. For instance, the blood alcohol concentration can be used to modify the biochemistry of methanol and ethylene glycol. Also the rate-limiting steps for one substance may be in common with other substances. Hence the removal of a large concentration of alcohol from blood may follow zero-order kinetics. The removal of ethanol ( alcohol) through oxidation by alcohol dehydrogenase in the liver from the human body is limited. The basis of this decontamination method (used at Harwell) is to increase the rate at which the water in the body is replaced with new water. Drinking the same amount of water would have a similar effect, but many would find it difficult to drink a large volume of water. This has been used to decontaminate humans who are internally contaminated with tritiated water ( tritium). Drinking large amounts of alcohol will reduce the biological half-life of water in the body. The biological half-life of water in a human is about 7 to 10 days.
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